FREE RADICALS IN HEART MUSCLE MITOCHONDRIAL PARTICLES: MECHANISM OF FORMATION
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چکیده
منابع مشابه
Free Radicals in Heart Muscle Mitochondrial Particles: Mechanism of Formation.
thereby initiating a rapid change in the fumarate/succinate ratio, the free radical concentration increases to a maximum and then declines to zero Our results suggest, therefore, that the free radicals observed in heart particles arise from equilibrium processes catalyzed by succinic dehydrogenase and that their steady-state concentration is governed by the parameters which affect this equilibr...
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Electron paramagnetic resonance (EPR) spectroscopy can be applied to directly measure free radicals; however, it has not been possible to measure important biologic radicals in situ because conventional spectrometer designs are not suitable for the performance of measurements on large aqueous structures such as whole organs or tissues. We describe the design, construction, and application of in...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1960
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.46.4.416